Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target HMGB1 (clone 31G6Z1G). We employs the pGEX (CMV-mCherry-IL-10-SaII) vector components and the SynExpress system of the Multiple base pair Insertion/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
HMGB1
Clone
31G6Z1G
Species Reactivity
Human; Mouse
Cell Source
Synthetic CD4+ T cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
IL-10
Insertion Sites
SaII
Gene Modification
Insertion
Modification Domain
Multiple base pair
Carrier Type
pGEX
Transformation Accuracy
0.86
Cell Culture
Adherent Culture

For Research Use Only | Not For Clinical Use

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