Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target KDR (clone IO6Z.6Z4I). We employs the pCDNA (CMV-mNeonGreen-IL-4-KpnI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Chimeric (mouse/human)
Target
KDR
Clone
IO6Z.6Z4I
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mNeonGreen
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
pCDNA
Transformation Accuracy
0.85
Cell Culture
3D Culture

For Research Use Only | Not For Clinical Use

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