Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target LeY (clone BR5L5L-2E). We employs the AAV (SV40-YFP-c-Jun-KpnI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
LeY
Clone
BR5L5L-2E
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
YFP
Promoter
SV40
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.99
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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