Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target MS4A1 (clone 1G.5L.3). We employs the AAV (SV40-Cy2-c-Jun-HindIII) vector components and the SynExpress system of the lncRNA Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Humanized
Target
MS4A1
Clone
1G.5L.3
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
Cy2
Promoter
SV40
Effector Gene
c-Jun
Insertion Sites
HindIII
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.9
Cell Culture
Suspension Culture

For Research Use Only | Not For Clinical Use

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