Short Decsription
This product is a Carbon-oxygen lyases-targeted RNA modification and metabolomics analysis tool based on the m7G (TRMT6/61A-YTHDF1/2/3-ALKBH7-HDACs-spacer C18) modification and Glycolysis-mediated (hnRNPs-SAM-ATP) metabolic analysis system.
RNA writers
TRMT6/61A
RNA readers
YTHDF1/2/3
RNA erasers
ALKBH7
Enzymes
HDACs
RNA types
rRNA
Modification
m7G
Label
spacer C18
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
cET, 2'-MOE
RNA Construction
rRNA-m7G-TRMT6/61A-YTHDF1/2/3-ALKBH7-HDACs-spacer C18
Substrates
SAM
Cofactors
ATP
Pathway
Glycolysis
Epigenetic regulator
LKB1 deficiency
Metabolic alteration
The formation of an "adenosine rich" suppressive TME
Targeting diseases
Colorectal Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Glycolysis-hnRNPs-SAM-ATP

For Research Use Only | Not For Clinical Use

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