Short Decsription
This product is a Carbon-sulfur lyases-targeted RNA modification and metabolomics analysis tool based on the m1A (NSUN1-ALYREF-ALKBH1-HDACs-spacer C9) modification and Mevalonate pathway-mediated (hnRNPs-Lactyl-CoA-NAD+) metabolic analysis system.
RNA writers
NSUN1
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
HDACs
RNA types
mRNAs
Modification
m1A
Label
spacer C9
RNA editing
A to I
Cell Type
M2 macrophages
Oligonucleotide
cET
RNA Construction
mRNAs-m1A-NSUN1-ALYREF-ALKBH1-HDACs-spacer C9
Substrates
Lactyl-CoA
Cofactors
NAD+
Pathway
Mevalonate pathway
Epigenetic regulator
ARID1A deficiency
Metabolic alteration
Inhibiting reduced glutathione synthesis
Targeting diseases
Adrenocortical carcinoma
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-Lactyl-CoA-NAD+

For Research Use Only | Not For Clinical Use

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