Description
CTLA4 or CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152 (cluster of differentiation 152), is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses. CTLA4 is constitutively expressed in Tregs but only upregulated in conventional T cells after activation. It acts as an `off` switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.
Organism
mouse
Strain Name
CHO-K1
Common Name
Cd152; Ly-56; Ctla-4

For Research Use Only | Not For Clinical Use

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