Short Decsription
Creative Biolabs offers Chromogenic LAL Assay-2040 tests, 0.005 to 50 EU/mL designed to advance your cancer research.
Description
PharmaOnco™ Chromogenic LAL Assay-2040 tests, 0.005 to 50 EU/mL is designed for endotoxin detection by chromogenic method in samples.
Features
Most sensitive LAL-based method; Less sensitive to product inhibition
Applications
Endotoxin Detection
Molecular Mechanism of Action
LAL test relys on factor C coagulation cascade found in horseshoe crabs' blood. The combination of endotoxin and zymogen factor C initiate the protease cascade. Next, the activated factor C goes onto activate factor B, which converts the proclotting enzyme to the clotting enzyme. Lastly, two peptide bonds in coagulogen are catalytically cleaved to form coagulin gel.
Qualified With
Quality Certificate
Detection Method
Chromogenic
Method Type
Lyophilized amebocyte lysate (LAL)
Datasheet