Histology Assay - Gastric ulcer tissue microarray, 14 Cases/24 Cores (CAT#: ITS-1022-ZP705)

Creative Biolabs has expertise in sample preparation for Immuno-Oncology histology services and immunohistochemistry (IHC). We understand that not all tissues are suitable for Immuno-Oncology studies. To support the specific tissue requirements for Immuno-Oncology projects, we have created a large range of FFPE blocks and custom Tumor Microarrays (TMAs) that have been specially selected for the presence of invasive margin, together with accompanying tumor/immune cell PD-L1 scores and TIL assessment (high/medium/low).

The services we provide as part of our Histology & IHC Platform are listed below:
- Standard & custom grossing
- Bone decalcification
- Standard & custom FFPE generation
- H&E Staining
- Marker optimization for IHC
- Slide Scanning
- TMA creation

Creative Biolabs Immuno-Oncology's histology and immunohistochemistry assay are custom developed and fully optimized to meet your needs in preclinical research. We also provide a comprehensive list of antibodies for IHC for your histology research. Contact us for more information.

- Expression, distribution and heterogeneity of novel I/O targets across multiple disease settings
- Examine novel I/O target expression in relation to tumor immune microenvironment e.g. checkpoint inhibitors
- Spatial relationships of I/O in tumor microenvironment
- Relate novel I/O target expression to tumor mutation status
- Identify disease segments most likely to respond toimmunotherapy
- Co-expression of I/O targets for rational immunotherapy combinations
- Biomarker development for patient selection

Routine histology procedures including Immunohistochemistry (IHC) and In Situ Hybridization (ISH)

Optimised IHC assay offerings, novel monoplex and duplex assay development, quantitative image analysis and RNAScope®. Technologies can be applied to:
- Further immune infiltrate analyses
- Comparative PD-L1/PD-1 evaluation
- Study of customer specified immune signatures and novel targets