Product Overview
16,16-Dimethyl-prostaglandin E2 (16,16-dimethyl PGE2) is an antisecretory, antiulcer PGE2 analog that is resistant to metabolism. It is an active vertebrate Hematopoietic stem cells (HSCs) homeostasis critical regulator and induces an increase in HSC numbers. 16,16-dimethyl PGE2 can act through EP2/EP4 and has an interaction with the Wnt pathway.
Applications
Cell Expansion and Differentiation
Chemical Name
(5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid
Cell Type
Hematopoietic Stem and Progenitor Cells
Area of Interest
Immunology
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.