Product Overview
BMS 493 is a pan-retinoic acid receptor (pan-RAR) inverse agonist. This compound has been shown to increase nuclear corepressor (NCoR) interaction with RARs. RAR controls a number of physiological processes including cell growth, differentiation, survival, and death.
Applications
Inverse Agonist of pan-RAR, Cell Expansion and Differentiation
Chemical Name
4-[(1E)-2-[5,6-Dihydro-5,5-dimethyl-8-(2-phenylethynyl)-2-naphthalenyl]ethenyl]benzoic acid
Cell Type
Airway Cells, Cancer Cells and Cell Lines, Hematopoietic Stem and Progenitor Cells, Monocytes
Species
Human, Mouse, Rat, Non-Human Primate, Other
Area of Interest
Immunology, Infectious Diseases,Cancer, Gene therapy
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Datasheet