Product Overview
Collagenase is a protease that cleaves the bond between a neutral amino acid (X) and glycine in the sequence Pro-X-Glyc-Pro, which is found with high frequency in collagen. Collagenase Type IV (gelatinase) has a marked substrate specificity for denatured collagen (gelatin). Collagenase Type IV contains low levels of tryptic activity and is frequently used for pancreatic islets and for applications where maintenance of receptor integrity is required.
Applications
Mammalian Cell Culture; Release of cells from animal tissues
Cell Type
Cardiomyocytes, PSC-Derived, Epithelial Cells, Mammary Cells, Mesenchymal Stromal Cells
Source
Clostridium histolyticum
Area of Interest
Immunology, Stem Cell Biology
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Datasheet