Product Overview
Deoxyribonuclease I (DNase I, encoded by DNASE1) is a specific endonuclease facilitating chromatin breakdown during apoptosis. It is a versatile enzyme that nonspecifically cleaves DNA to release 5'-phosphorylated di-, tri-, and oligonucleotide products. DNase-I is appropriate for tissue digestion and preparation of a single cell suspension, and has been used for the digestion of human tissues such as microglia , cartilage, colon, epithelium, liver, lung, neural , and stem cells.
Applications
Digestion of DNA
Cell Type
B Cells, Endothelial Colony Forming Cells (ECFCs), Neurons, Osteoblasts, T Cells
Area of Interest
Immunology, Stem Cell Biology
Limitation
Restrictions for research use only. Intended for use by laboratory professionals.
Datasheet