PharmaOnco™ Jurkat-NF-κB Luc Reporter Cell Line, Single Clone (CAT#: ITS-0822-HMM182)

Creative Biolabs offers Jurkat-NF-κB Luc reporter cell line which has been engineered to express a luciferase reporter gene under the control of the NF-κB signaling pathway.

The Jurkat-NF-κB Luc reporter cell line is a specialized cell line that has been engineered to express a luciferase reporter gene under the control of the NF-κB signaling pathway. NF-κB is a transcription factor that plays a critical role in regulating the expression of genes involved in inflammation, immunity, and cell survival.

Consistent gene expression;
Reliability and reproducibility;

Functional assay

Jurkat

NF-κB Luc Reporter is a type of reporter gene construct that contains a luciferase gene under the control of NF-κB transcription factor binding sites. This reporter system is used to study the activation of the NF-κB pathway, which plays a critical role in regulating the expression of genes involved in inflammation, immunity, and cell survival. By measuring the activity of the luciferase enzyme, researchers can determine the level of NF-κB activation in response to various stimuli and treatments. This reporter system is widely used in cell culture and animal studies to investigate the signaling pathways that regulate NF-κB activation and its downstream effects.