LAG3 (Human) Activator/Inhibitor Screening Assay, Jurkat (LAG3 & NFAT-Luc)-based (CAT#: ITS-1122-LX201)

Jurkat

Human

Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human LAG3 (lymphocyte-activation gene 3, CD223, GenBank Accession #NM_002286) Which can be used in binding assays and functional assay.

Jurkat (LAG3 & NFAT-Luc)

Cancer

Oncology

In Vitro Activator/Inhibitor Screening Assay

Screen for activators or inhibitors of LAG3 signaling in a cellular context and characterize the biological activity of LAG3 and its interactions with ligands.

Creative Biolabs has developed several I-O function assay based on our stable cell Lines expressed the most popular immune checkpoints. LAG3 (Human) Activator/Inhibitor Screening Assay, Jurkat (LAG3 & NFAT-Luc)-based is applied to screen for activators or inhibitors of LAG3 signaling in a cellular context and characterize the biological activity of LAG3 and its interactions with ligands. The assay will be customized according to the client's specific requirements. Please contact our scientists to discuss more details.

In Vitro Activator/Inhibitor Screening Assay; Activator/Inhibitor Screening Assay

NFAT-Luciferase Reporter

Activator/Inhibitor Screening Assay

Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human LAG3 (lymphocyte-activation gene 3, CD223, GenBank Accession #NM_002286) Which can be used in binding assays and functional assay.