LS411N In Vitro SRB Assay (Cell Viability) (CAT#: ITS-1122-YF428)

LS411N

Human

LS411N is a colorectal carcinoma cell line isolated in 1985 from a primary tumor biopsy of a Dukes' B, poorly differentiated cecal carcinoma.
The cells obtained after passage in nude mice are referred to as LS411N cells.

Colorectal Adenocarcinoma; Colon Cancer

Oncology

In Vitro SRB Assay (Cell Viability)

LS411N-cell based In Vitro SRB Assay (Cell Viability)

The sulforhodamine B is another common colorimetric assay that is used to investigate viability of cancer cells. The dye SRB can bind with proteins in viable cells under mild acidic conditions, and the bound dye is finally solubilized to get absorbance at 500-540 nm.

Sulforhodamine B Assay

Cell Viability/Cytotoxicity and Antiproliferative Assays

Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.

Cell Viability Assay

Cell-based Viability Assays Based on Cellular Enzymes and Proteins