Short Decsription
This product is a MCAT-targeted RNA modification and metabolomics analysis tool based on the m6Am (METTL3-YTHDC1-ALKBH5-ACOT12-phos) modification and Fatty acid synthesis-mediated (PRPF8-Lactyl-CoA-ATP) metabolic analysis system.
RNA Construction
mRNAs-m6Am-METTL3-YTHDC1-ALKBH5-ACOT12-phos
Pathway
Fatty acid synthesis
Epigenetic regulator
SMARCA4 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation
Targeting diseases
Acute Myeloid Leukemia
RNA-binding proteins
PRPF8
Metabolic Reprogramming
Fatty acid synthesis-PRPF8-Lactyl-CoA-ATP