Alternative Name
Interleukin 1 Beta (IL1b)
Synonyms
IL-1; IL1-BETA; IL1F2; IL-1BETA; IL1beta; il1-b; zgc:111873; IL-1B; IL-1beta; Il-1b; IL1B; IL-1 beta; IL-1b; interleukin 1 beta; interleukin 1; beta; IL1B; il1b; Il1b
Background
Interleukin-1 beta (IL-1β) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. It is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol.
Pathways
IL-1 signaling pathway, NF-κB signaling pathway, MAPK signaling pathway, JAK-STAT signaling pathway, TLR signaling pathway, NLR signaling pathway, Inflammasome activation pathway, Cytokine-cytokine receptor interaction, Apoptosis pathway, Pyroptosis pathway, Immune response modulation, Cell proliferation and differentiation, Angiogenesis pathway, Chemokine signaling pathway.