NCI-H596 In Vitro LDH Assay (Cell Viability) (CAT#: ITS-0123-YF115)

NCI-H596

Human

The NCI-H596 cell line was derived by A.F. Gazdar and H. Oie in 1983 from a tumor mass in the chest wall of a patient with adenosquamous carcinoma of the lung. The specimen was obtained prior to therapy.

Adenosquamous Carcinoma

Oncology

In Vitro LDH Assay (Cell Viability)

Lactate dehydrogenase leakage assay (LDH assay) can also be used to determine viability of cancer cells. Upon treatment with a testing drug, if the drug can rupture the cell membrane, cells release LDH to the culture medium and released LDH can be quantified.

Lactate Dehydrogenase Leakage Assay

Cell Viability/Cytotoxicity and Antiproliferative Assays

Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.

Cell Viability Assay

Cell-based Viability Assays Based on Cellular Enzymes and Proteins