Short Decsription
This product is a OGDH-targeted RNA modification and metabolomics analysis tool based on the m1A (DNMT2-ALYREF-ALKBH1-ACOT12-phos) modification and Mevalonate pathway-mediated (hnRNPs-Lactyl-CoA-ADP) metabolic analysis system.
RNA writers
DNMT2
RNA readers
ALYREF
RNA erasers
ALKBH1
Enzymes
ACOT12
RNA types
rRNA
Modification
m1A
Label
phos
RNA editing
A to I
Cell Type
M1 macrophages
Oligonucleotide
2'-OMe (cationic lipoplex)
RNA Construction
rRNA-m1A-DNMT2-ALYREF-ALKBH1-ACOT12-phos
Substrates
Lactyl-CoA
Cofactors
ADP
Pathway
Mevalonate pathway
Epigenetic regulator
ACLY overexpression
Metabolic alteration
Increasing the content of acetyl-CoA
Targeting diseases
Lung Cancer
RNA-binding proteins
hnRNPs
Metabolic Reprogramming
Mevalonate pathway-hnRNPs-Lactyl-CoA-ADP

For Research Use Only | Not For Clinical Use

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