Short Decsription
This product is a ready-to-use IHC kit for staining of CASP7. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.
Description
Caspase 7(CASP7), like caspases 3 and 6, contains a short prodomain and, upon apoptotic induction, proform is converted into a intermediate or preactive form which is further processed into two active subunits consisting of the p20 or large subunit and the p10 or small subunit and it is present in the brain, which is up-regulated and activated after traumatic injury. Caspase-7 is classified as a member of the subgroup of cysteine proteases most related to the Caenorhabditis elegans factor CED-3, which also includes caspase-3, -6, and -9. The protein is involved in the activation cascade of caspases responsible for apoptosis execution.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet