Short Decsription
Simplify CD105 visualization with this IHC kit that includes all reagents for a seamless staining procedure, from antigen retrieval to coverslipping.
Description
Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein composed of disulphide-linked subunits of 95 kDa. It is mainly expressed on vascular endothelial cells and acts as an accessory receptor for transforming growth factor beta (TGF-β), involved in vascular development and remodeling. Endoglin plays a crucial role in angiogenesis and tumor progression, making it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Analytical Method
Immunohistochemistry