Short Decsription
This complete IHC kit for DLK1 offers a direct approach to staining, equipping users with reagents from antigen retrieval to slide mounting.
Description
DLK1, also known as PREF1, FA1, or pG2, is a transmembrane protein from the EGF-like superfamily, containing six EGF-like repeats in its extracellular domain. DLK1 negatively regulates the differentiation of preadipocytes into adipocytes. In mouse models, DLK1 deficiency leads to growth delays and increased fat accumulation. It is also expressed in neuroendocrine tumors, suggesting it plays a role in neuroendocrine differentiation. Its overexpression may contribute to metabolic disturbances by impairing adipocyte function in mice.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet