Short Decsription
Facilitate DSG2 detection using this ready-to-deploy IHC solution, encompassing reagents from antigen retrieval to slide preparation.
Description
Desmosomal cadherins are integral to the function of desmosomes, which are essential for the adhesion of epithelial, myocardial, and other cell types. DSG2 is a transmembrane glycoprotein found in a wide range of tissues, including the heart, intestine, and epidermis. Mutations in DSG2 are associated with familial arrhythmogenic right ventricular dysplasia (ARVD10) and susceptibility to dilated cardiomyopathy.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Analytical Method
Immunohistochemistry