Short Decsription
Ensure consistent Histone H1.0 staining with this pre-prepared IHC kit, supplying reagents tailored for efficient, start-to-finish staining.
Description
Histones are fundamental nuclear proteins essential for the formation of nucleosomes, the structural units of chromosomal fibers in eukaryotic cells. Nucleosomes consist of approximately 146 base pairs (bp) of DNA wrapped around a histone octamer, which includes two copies of each of the four core histones: H2A, H2B, H3, and H4. Linker histone H1 interacts with the DNA between nucleosomes, facilitating the formation of higher-order chromatin structures. Linker histones, such as H1F0, are critical for maintaining chromatin compaction, especially in cells that are in the terminal stages of differentiation or have low cell division rates. H1.0 (also known as H1F0 or H1FV) is ubiquitously expressed in various tissues across vertebrates.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet