Short Decsription
Simplify IGF2BP1 staining with this comprehensive IHC kit, featuring pre-optimized reagents for a straightforward antigen retrieval to mounting procedure.
Description
IGF2BP1 (CRDBP, VICKZ1, ZBP1) is a 577 amino acid protein in the RRM IMP/VICKZ family. It forms homodimers and heterodimers with IGF2BP1 and IGF2BP3. IGF2BP1 is mainly expressed in the embryo (fetal liver, lung, kidney, thymus) and in gonocytes, testis, spermatogonia, semen, oocytes, and placenta. It is expressed in cancers, including testis, lung, kidney, prostate, and trachea. IGF2BP1 is an RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes, shielding them from degradation.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet