Short Decsription
Ensure consistent Integrin alpha-1 staining with this pre-prepared IHC kit, supplying reagents tailored for efficient, start-to-finish staining.
Description
Integrins are a large family of cell adhesion receptors that bind extracellular matrix ligands, cell-surface ligands, and soluble ligands. These transmembrane αβ heterodimers form at least 24 distinct combinations of 18 α-subunits and eight β-subunits. In addition to mediating cell adhesion, integrins are crucial for signaling pathways that regulate cellular processes such as migration, proliferation, differentiation, and apoptosis. Integrin alpha-1 (ITGA1, CD49a) pairs with beta-1 (ITGB1, CD29) to form a receptor that mediates cell adhesion to collagen and laminin, playing a role in inflammation and fibrosis.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Analytical Method
Immunohistochemistry
Datasheet