Short Decsription
Simplify PDK1 staining with this comprehensive IHC kit, featuring pre-optimized reagents for a straightforward antigen retrieval to mounting procedure.
Description
PDK1 (3-Phosphoinositide-dependent protein kinase-1), also known as PDPK1, is a serine-threonine kinase of the AGC kinase family. It plays a crucial role in asymmetric cell division (ACD) in epithelial cells. Its kinase activity depends on phosphatidylinositol 3-kinase (PI3K), which mediates signaling from growth factor receptors and adhesion molecules. PDK1 substrates, including AKT and PKC isozymes, regulate essential cellular functions.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry