Short Decsription
Streamline PSME2 staining procedures with this all-inclusive IHC kit, pre-formulated with reagents for a complete workflow.
Description
The proteasome is responsible for the targeted degradation of intracellular proteins, and its activity is regulated by complexes that bind to the proteasome's ends. The 11S regulator (REG or PA28) complex activates proteasomes for the production of antigenic peptides. Human PSME1 and PSME2 encode the PA28 alpha and beta activators, respectively, which are involved in antigen processing and loading class I MHC molecules. These activators enhance class I peptide generation by altering the proteasome's cleavage pattern.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry
Datasheet