Short Decsription
This complete IHC kit for PTEN offers a direct approach to staining, equipping users with reagents from antigen retrieval to slide mounting.
Description
PTEN (Phosphatase and Tensin Homolog, MMAC1, TEP1) is a tumor suppressor that regulates cell cycle progression and survival by downregulating cyclin D1 and upregulating p21. It plays a critical role in cancer development, and its inactivation is frequent in cancers, second only to p53 mutations.
Features
Ready to use
High Sensitivity Streptavidin (HSS) increases detection sensitivity
Suitable for tissue sections & cytospin preparations
Pre-diluted reagents minimize hands-on time
Optimizes mouse, rabbit, rat, goat, or sheep IgG primary antibody staining
Reactivity
Human, Mouse, Rat
Analytical Method
Immunohistochemistry