Assay Name
In Vitro Activator/Inhibitor Screening Assay
Short Description
Screen for activators or inhibitors of PD-1 signaling in a cellular context , screen PD-L1 antibodies for binding affinity.
Assay Description
Creative Biolabs has developed several I-O function assay based on our stable cell Lines expressed the most popular immune checkpoints. PD-L1 (Human) Activator/Inhibitor Screening Assay, CHO-K1 (PD-L1 & TCR Activator)-based is applied to screen for activators or inhibitors of PD-1 signaling in a cellular context , screen PD-L1 antibodies for binding affinity. The assay will be customized according to the client's specific requirements. Please contact our scientists to discuss more details.
Assay Alternative Names
In Vitro Activator/Inhibitor Screening Assay; Activator/Inhibitor Screening Assay
Assay Reporter
TCR Activator
Assay Type
Activator/Inhibitor Screening Assay
Assay MOA
Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant CHO-K1 cells constitutively expressing human PD-L1 (Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7- H1), GenBank accession # NM_014143) an engineered T cell receptor (TCR) activator. Which can be used in binding assays and functional assay.
Datasheet