Short Decsription
This product is a Ribulose 5-phosphate-targeted RNA modification and metabolomics analysis tool based on the m1A (METTL3-YTHDF1-FTO-KMTs-BHQ1) modification and Mevalonate pathway-mediated (FMRP-Succinyl-CoA-α-KG) metabolic analysis system.
RNA writers
METTL3
RNA readers
YTHDF1
RNA erasers
FTO
Enzymes
KMTs
RNA types
rRNA
Modification
m1A
Label
BHQ1
RNA editing
G to A
Cell Type
DCs
Oligonucleotide
2'-MOE
RNA Construction
rRNA-m1A-METTL3-YTHDF1-FTO-KMTs-BHQ1
Substrates
Succinyl-CoA
Cofactors
α-KG
Pathway
Mevalonate pathway
Epigenetic regulator
SETD2 deficiency
Metabolic alteration
Upregulating oxidative phosphorylation andfatty acid synthesis
Targeting diseases
Hepatocellular Carcinoma
RNA-binding proteins
FMRP
Metabolic Reprogramming
Mevalonate pathway-FMRP-Succinyl-CoA-α-KG

For Research Use Only | Not For Clinical Use

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