TALL-104 In Vitro Calcein AM Cytotoxic Assay (Cell Viability) (CAT#: ITS-1122-YF5467)

TALL-104

Human

TALL-104 is a T lymphoblast cell line that was established from the peripheral blood of a two-year-old male child in relapse with T-ALL. Applications include immune system disorder, immunology, and immuno-oncology research.

Acute Lymphoblastic Leukemia; ALL

Oncology

In Vitro Calcein AM Cytotoxic Assay (Cell Viability)

TALL-104-cell based In Vitro Calcein AM Cytotoxic Assay (Cell Viability)

Calcein AM is another non-fluorescent cell permeable dye, which is converted to green-fluorescent calcein by viable intracellular esterases. Calcein violet AM, calcein red-orange, Oregon green 488 and 5-CFDA-AM are other examples of dyes used to monitor cell viability based on esterase activity in viable cells.

Cell Viability/Cytotoxicity and Antiproliferative Assays

Uncontrolled proliferation is one of the main features of cancer cells. Cell-based in vitro assays are employed to determine whether test molecules possess direct cytotoxic/antiproliferative effects in cancer cells.

Cell Viability Assay

Cell-based Viability Assays Based on Cellular Enzymes and Proteins