Short Decsription
Creative Biolabs offers Turbidimetric LAL Assay (with endotoxin)-128 tests; 0.01 to 10 EU/mL; 0.05 to 5 EU/mL designed to advance your cancer research.
Description
PharmaOnco™ Turbidimetric LAL Assay (with endotoxin)-128 tests; 0.01 to 10 EU/mL; 0.05 to 5 EU/mL is designed for endotoxin detection by turbidimetric method in samples.
Features
Sensitivity could reach 0005 EU/mL
Applications
Endotoxin Detection
Molecular Mechanism of Action
LAL test relys on factor C coagulation cascade found in horseshoe crabs' blood. The combination of endotoxin and zymogen factor C initiate the protease cascade. Next, the activated factor C goes onto activate factor B, which converts the proclotting enzyme to the clotting enzyme. Lastly, two peptide bonds in coagulogen are catalytically cleaved to form coagulin gel.
Qualified With
Quality Certificate
Detection Method
Turbidimetric
Method Type
Lyophilized amebocyte lysate (LAL)
Datasheet