E3 Ligase and Target Protein Products

Protein Degraderss degrade the disease-causing proteins by hijacking the ubiquitin-proteasome system (UPS). Unlike traditional small-molecule inhibitors, Protein Degraderss provide a better and more efficient strategy. During the discovery process of an efficient Protein Degraders molecule, multiple parameters and details need to be optimized and designed, such as the affinity of Protein Degraders molecules to target proteins and to the E3 ligase proteins. Besides, although there are nearly 600 ligases identified in the human genome, many of them remain relatively uncharacterized. To reveal their substrates, in vitro high-throughput screening with purified E3 ligase is an approach. To make it possibly easier to fulfill the optimization and the characterization, Creative Biolabs produces several proteins including E3 ligases and target proteins as products.

Bromodomain-containing Protein 4(CAT#: PRLP-001)

Datasheet INQUIRY

Type: Target protein

Size: 0.1 mg

a.a:

E3 Ubiquitin-Protein Ligase MDM2(CAT#: PRLP-002)

Datasheet INQUIRY

Type: E3 ligase protein

Size: 0.02 mg

a.a: