An intact Protein Degraders molecule consists of 3 components, a ligand for target proteins, a linker, and a ligand against E3 ubiquitin ligase. Ligand-linker conjugates are chemical molecules that a linker molecule linked to the ligand against target proteins or against the E3 ubiquitin ligase. The binding affinities may be altered by additional chemical structures, therefore, with this type of product, the properties of ligands and linkers could be evaluated at the same time and have much close results with an intact Protein Degraders molecule. Besides, with the same functional ligands conjugated with different linkers, the compounds have advantages in functional comparison and subsequent screening. In addition, the ligand-linker conjugates decrease the amount of time spent on Protein Degraderss synthesis. Below Creative Biolabs listed alkyl-chains, PEGs, alkyl/ethers linked ligand-linker conjugates with various ligands. All these partial Protein Degraders molecules have high solubility in DMSO or other appropriate solvents.
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us