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- Anti-CD4 MAb (Clone 11)-iFluor® 450 Succinimidyl Ester
Anti-CD4 MAb (Clone 11)-iFluor® 450 Succinimidyl Ester (CAT#: WJY0-LS7296)
This product is comprised of an Human Anti-CD4 IgG1-kappa/lambda (Clone 11) labeled with iFluor® 450 Succinimidyl Ester. iFluor® 450 Succinimidyl Ester is a Green-fluorescent dye and it's excitation/emission is 403/427 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- CD4
- Alternative Names
- CD4; CD4 molecule; CD4 antigen (p55) ; T cell surface glycoprotein CD4; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3; CD4mut;
- Overview
- This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
- Overview
- Human Anti-CD4 IgG1-kappa/lambda (Clone 11)
- Species Reactivity
- Human
- Name
- iFluor® 450 Succinimidyl Ester
- Color
- Green
- Excitation⁄Emission (nm)
- 451/502
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-881 | Anti-CD4 (Clenoliximab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
| ADC-W-884 | Anti-CD4 (Cedelizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-892 | Anti-CD4 (Ibalizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-886 | Anti-CD4 (Cedelizumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-885 | Anti-CD4 (Cedelizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
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