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- Anti-IL1B MAb (Clone 6)-iFluor® 350 Succinimidyl Ester
Anti-IL1B MAb (Clone 6)-iFluor® 350 Succinimidyl Ester (CAT#: WJY0-LS1325)
This product is comprised of an Humanized Anti-IL1B [VH-VH'-H-Gamma1_VL-VL'-C-kappa]-dimer (Clone 6) labeled with iFluor® 350 Succinimidyl Ester. iFluor® 350 Succinimidyl Ester is a Blue-fluorescent dye and it's excitation/emission is 345/450 nm.
- TARGET
- ANTIBODY
- DYE
- Name
- IL1B
- Alternative Names
- IL1B; IL-1; IL1-BETA; IL1F2; interleukin 1 beta; IL1beta
- Overview
- Interleukin 1β (IL-1β) is also known as leukocyte pyrogen, endogenous leukocyte mediator, monocyte factor, lymphocyte activating factor, etc. It is a cytokine protein encoded by IL1B gene in humans. Interleukin 1 (IL-1) has two genes: IL-1 alpha and IL-1 beta (the gene). The IL-1β precursor is cleaved by cytoplasmic cysteine protease 1 (interleukin 1β converting enzyme) to form mature IL-1β.
- Overview
- Humanized Anti-IL1B [VH-VH'-H-Gamma1_VL-VL'-C-kappa]-dimer (Clone 6)
- Species Reactivity
- Human
- Name
- iFluor® 350 Succinimidyl Ester
- Color
- Blue
- Excitation⁄Emission (nm)
- 345/450
- Detection method
- Fluorescent
For Research Use Only. NOT FOR CLINICAL USE.
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| CAT# | Product Name | Linker | Payload |
| ADC-W-1328 | Anti-IL1B (Gevokizumab)-SMCC-DM1 ADC | SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) |
| ADC-W-1336 | Anti-IL1B (Canakinumab)-MC-MMAF ADC | MC (maleimidocaproyl) | MMAF |
| ADC-W-1335 | Anti-IL1B (Canakinumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1329 | Anti-IL1B (Gevokizumab)-SPDB-DM4 ADC | SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate) | DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine) |
| ADC-W-1337 | Anti-IL1B (Canakinumab)-MC-Vc-PAB-MMAE ADC | MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) | MMAE |
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