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Cordycepin (CAT#: ADC-P-075)
ADCs Toxins, Cordycepin from Cordyceps militaris. Cordycepin blocks revovery of non-heat-shock mRNA translation following heat shock in Drosophilla. Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotide transferase-positive leukemic cells has been reported. Cordycepin blocks the Smad signaling by 3`-deoxyadenosine (a mechanism for its anti-fibriotic potential).
- Product Information
- CAS NO
- 73-03-0
- Description
- ADCs Toxins, Cordycepin from Cordyceps militaris. Cordycepin blocks revovery of non-heat-shock mRNA translation following heat shock in Drosophilla. Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotide transferase-positive leukemic cells has been reported. Cordycepin blocks the Smad signaling by 3`-deoxyadenosine (a mechanism for its anti-fibriotic potential).
- Classification
- RNA inhibitors
- Molecular Weight
- 251.24
- Purity
- 95%
For Research Use Only. NOT FOR CLINICAL USE.
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Customer Reviews
FAQ
Excellent
Cordycepin proved to be highly effective in our leukemia cell studies, showing significant antileukemic activity. Its ability to block Smad signaling provided valuable insights into its anti-fibrotic potential.
Excellent
We used Cordycepin in ADC research and found it to be a potent toxin for targeting leukemic cells. Its antileukemic mechanism enhanced the efficacy of our antibody-drug conjugates.
Excellent
In our mRNA translation experiments with Drosophila, Cordycepin effectively blocked recovery after heat shock. This made it a useful tool for studying stress response pathways in cells.
Excellent
Cordycepin played a crucial role in our ADC development, exhibiting strong cytotoxic effects against TdT-positive leukemic cells. Its potential in targeted cancer therapies is promising.
Excellent
Cordycepin enhanced the antileukemic activity of our ADCs, especially in leukemic cells expressing terminal deoxynucleotide transferase. Its inclusion in our drug conjugates significantly boosted cytotoxicity.
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