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DBCO-acid (CAT#: ADC-L-317)
DBCO-Acid is a non-activated building block and adds minimal spacer to modified molecules. In the presence of activators such as EDC or HATU, this reagent can be used to derivatize amine-containing molecules through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions.
- Product Information
- CAS NO
- 1353016-70-2
- Description
- DBCO-Acid is a non-activated building block and adds minimal spacer to modified molecules. In the presence of activators such as EDC or HATU, this reagent can be used to derivatize amine-containing molecules through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions.
- Molecular Weight
- 305.3
- Purity
- 95%
- Formula
- C19H15NO3
- Group 1
- DBCO
- Click Chemistry Group 1
- DBCO
- PEG/Non-PEG
- Non-PEG
- Cleavable/Non-cleavable
- Non-cleavable
- Group 2
- COOH/Carboxylic Acid
- Functional Group 2
- COOH/Carboxylic Acid
- Storage Condition
- -20 ° C
- Shipping
- Ambient Temperature
For Research Use Only. NOT FOR CLINICAL USE.
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Customer Reviews
FAQ
Excellent
In ADC research, DBCO-acid offered precise control over the attachment of small molecules to antibodies. The product's efficiency in conjugation made it an essential component in our drug development workflow.
Excellent
We used DBCO-acid for small molecule modification, and it performed exceptionally well. The reaction was clean, and the acid group enabled further functionalization, allowing us to tailor our conjugates for specific applications.
Excellent
DBCO-acid was critical in our ADC research, providing a reliable click chemistry mechanism. The acid group allowed us to introduce additional modifications to our payloads, improving the stability and efficacy of the final product.
Excellent
DBCO-acid contributed to the success of our ADC project by enabling efficient bioconjugation. The product's design facilitated quick and accurate attachment of cytotoxic payloads to our antibodies, enhancing the drug's overall potency.
Excellent
This linker worked effectively in our protein labeling studies. DBCO-acid allowed for seamless bio-conjugation while the acid group provided a functional handle for downstream modifications, making our workflow smoother.
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