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Ruplizumab-iFluor 405 (CAT#: ADC-FL-776)

This product is comprised of an anti-CD40LG monoclonal antibody (Ruplizumab) labeled with iFluor 405. iFluor 405 is a blue-fluorescent dye and it's excitation/emission is 401/421 nm.

  • TARGET
  • ANTIBODY
  • DYE
  • Name
  • CD40LG
  • Alternative Names
  • CD40LG; CD40 ligand; HIGM1, IMD3, TNFSF5, tumor necrosis factor (ligand) superfamily, member 5 (hyper IgM syndrome); CD40 antigen ligand; CD40L; CD154; gp39; hCD40L; hyper IgM syndrome; T B cell activating molecule; TNF related activation protein; TRAP; tnternalized inside cells, the cytosol provides reducing environment including intracellular enzyme protein disulfide isomerase, or similar enzymes, drugs can be released.
  • Overview
  • The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
  • Overview
  • Humanized Anti-CD40L IgG1-kappa antibody, Ruplizumab
  • Generic name
  • Ruplizumab
  • Species Reactivity
  • Human
  • Name
  • iFluor 405
  • Color
  • Blue
  • Excitation⁄Emission (nm)
  • 401/421
  • Detection method
  • Fluorescent

For Research Use Only. NOT FOR CLINICAL USE.

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ADC-W-922 Anti-CD40LG (Toralizumab)-MC-MMAF ADC MC (maleimidocaproyl) MMAF
ADC-W-2446 Anti-CD40LG (Dapirolizumab pegol)-MC-MMAF ADC MC (maleimidocaproyl) MMAF
ADC-W-917 Anti-CD40LG (Ruplizumab)-MC-Vc-PAB-MMAE ADC MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl) MMAE
ADC-W-920 Anti-CD40LG (Toralizumab)-SMCC-DM1 ADC SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate) DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)

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