Vapaliximab-PBlue (CAT#: ADC-FL-072)

This product is comprised of an anti-AOC3 monoclonal antibody (Vapaliximab) labeled with Pacific blue. Pacific blue is a blue-fluorescent dye and it's excitation/emission is 410/455 nm.

TARGET
ANTIBODY
DYE

Name
AOC3

Alternative Names
AOC3; amine oxidase, copper containing 3 (vascular adhesion protein 1); membrane primary amine oxidase; HPAO; VAP 1; VAP1; copper amine oxidase; vascular adhesion protein 1; semicarbazide-sensitive amine oxidase; SSAO; VAP-1;

Overview
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.

Overview
Chimeri Anti-AOC3 IgG2 antibody, Vapaliximab

Generic name
Vapaliximab

Species Reactivity
Human

Name
Pafific blue

Color
Blue

Excitation⁄Emission (nm)
410/455

For Research Use Only. NOT FOR CLINICAL USE.

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Scientific Resources

CAMouse™-Fully Human Antibody Generation Platform

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Customized ADCs

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Same Target

CAT#	Product Name	Linker	Payload
ADC-W-670	Anti-AOC3 (Vapaliximab)-MC-MMAF ADC	MC (maleimidocaproyl)	MMAF
ADC-W-675	Anti-AOC3 (Vepalimomab)-SPDB-DM4 ADC	SPDB (N-succinimidyl-4-(2-pyridyldithio)butyrate)	DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
ADC-W-676	Anti-AOC3 (Vepalimomab)-MC-MMAF ADC	MC (maleimidocaproyl)	MMAF
ADC-W-677	Anti-AOC3 (Vepalimomab)-MC-Vc-PAB-MMAE ADC	MC-Vc-PAB (maleimidocaproyl-valine-citrulline-p-aminobenzoyloxycarbonyl)	MMAE
ADC-W-673	Anti-AOC3 (Vapaliximab)-MC-Vc-PAB-DMEA-(PEG2)-duocarmycin SA ADC	MC-Vc-PAB-DMEA-(PEG2)	duocarmycin SA

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