shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(Lamtor2-shRNA-Seq1)(CAT#: AdV-SI4046WQ)

This product is a Lamtor2-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The protein encoded by Lamtor2 gene is highly conserved with a mouse protein associated with the cytoplasmic face of late endosomes and lysosomes. The expression of Lamtor2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype AdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Modification ΔE1/E3
Insert Lamtor2-shRNA-Seq1
Related Target/Protein Lamtor2
Region CDS
TargetSeq GCTGAATAATGAGGGATCGCT
NCBI RefSeq NM_031248
Alternative Names p14; ENDAP; ROBLD3; HSPC003; MAPBPIP; MAPKSP1AP; Ragulator2
Titer >1*10^10 GC/mL
Related Diseases Primary immunodeficiency syndrome
Target Gene
Gene ID 28956
Uniprot ID Q9Y2Q5

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