shRNA Adenovirus Serotype 5 (ΔE1/E3), p7SK-(TMEM156-shRNA-Seq1)(CAT#: AdV-SI1161WQ)

This product is a TMEM156-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. TMEM156 is expressed in several tissues including ascites, bone marrow, salivary glands, and vascular to name a few. It should be noted this gene is not ubiquitously expressed, but is still evident in many tissues. This gene is predominately expressed in adults but there is a bit of expression in fetuses. The expression of TMEM156-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Adenoviridae
Species Adenovirus
Serotype HAdV-5
Backbone AdV-5 (ΔE1/E3)
Tropism Both nondividing and dividing cells
Insert TMEM156-shRNA-Seq1
Related Target/Protein TMEM156
Region CDS
TargetSeq GAAGTGTGTTTGCAATCTAAT
NCBI RefSeq NM_024943
Titer >1*10^10 GC/mL
Related Diseases Breast cancer, liver cancer and prostate cancer
Target Gene
Gene ID 80008
Uniprot ID Q8N614

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