shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(HSPA13-shRNA-Seq2)(CAT#: AdV-SI0362WQ)

This product is a HSPA13-shRNA encoding AdV, which is based on AdV-5 serotype with EIB-55K gene deleted. The protein encoded by HSPA13 gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The expression of HSPA13-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.