shRNA Adenovirus Serotype 5 (ΔE1/E3), pU6-(Olfr380-shRNA-Seq1)(CAT#: AdV-SI2258WQ)
This product is a Olfr380-shRNA encoding AdV, which is based on AdV-5 serotype with E1/E3 gene deleted. The Olfr380 gene encodes a olfactory receptor protein that interacts with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The expression of Olfr380-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Adenoviridae |
Species | Adenovirus |
Serotype | AdV-5 |
Backbone | AdV-5 (ΔE1/E3) |
Tropism | Both nondividing and dividing cells |
Modification | ΔE1/E3 |
Insert | Olfr380-shRNA-Seq1 |
Related Target/Protein | Olfr380 |
Region | CDS |
TargetSeq | GCTGCCTGACACAAATGTACT |
NCBI RefSeq | NM_147025 |
Alternative Names | MOR135-1 |
Titer | >1*10^10 GC/mL |
Related Diseases | Olfactory dysfunction |