shRNA Lentivirus (self-inactivating), p7SK-(MORC2-shRNA-Seq1)(CAT#: LV-SI1377WQ)

This product is a MORC2-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The MORC2 gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The expression of MORC2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert MORC2-shRNA-Seq1
Related Target/Protein MORC2
Region CDS
TargetSeq CATCTATAAGTACTCTCCATT
NCBI RefSeq NM_014941
Alternative Names ZCW3; CMT2Z; ZCWCC1
Titer >1*10^10 GC/mL
Related Diseases Breast cancer
Target Gene
Gene ID 22880
Uniprot ID Q9Y6X9

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