shRNA Lentivirus (self-inactivating), p7SK-(NLRP9-shRNA-Seq2)(CAT#: LV-SI3216WQ)

This product is a NLRP9-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by NLRP9 gene belongs to the NALP protein family. This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. The expression of NLRP9-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert NLRP9-shRNA-Seq2
Related Target/Protein NLRP9
Region 3UTR
TargetSeq CGTCTCACAAAGGCTTTCCTT
NCBI RefSeq NM_176820
Alternative Names NOD6; NALP9; PAN12; CLR19.1
Titer >1*10^10 GC/mL
Related Diseases Immune system disease
Target Gene
Gene ID 338321
Uniprot ID Q7RTR0

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