shRNA Lentivirus (self-inactivating), pH1-(MTRF1L-shRNA-Seq1)(CAT#: LV-SI0867WQ)
This product is a MTRF1L-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by MTRF1L gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. The expression of MTRF1L-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.
Specifications | |
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Family | Retroviridae |
Species | Lentivirus |
Serotype | HIV-1 |
Backbone | Lenti-SIN |
Tropism | Both nondividing and dividing cells |
Insert | MTRF1L-shRNA-Seq1 |
Related Target/Protein | MTRF1L |
Region | CDS |
TargetSeq | CGGGTCACAGATCACAGAATA |
NCBI RefSeq | NM_019041 |
Alternative Names | MRF1L; HMRF1L; mtRF1a |
Titer | >1*10^10 GC/mL |