shRNA Lentivirus (self-inactivating), pH1-(Ptrh2-shRNA-Seq1)(CAT#: LV-SI3077WQ)

This product is a Ptrh2-shRNA encoding Lentivirus, which is based on HIV-1 serotype. The protein encoded by Ptrh2 gene is a mitochondrial protein with two putative domains and possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. The expression of Ptrh2-shRNA leads to target gene silencing and this product can be used in gene therapy research and development.

Specifications
Family Retroviridae
Species Lentivirus
Serotype HIV-1
Backbone Lenti-SIN
Tropism Both nondividing and dividing cells
Insert Ptrh2-shRNA-Seq1
Related Target/Protein Ptrh2
Region CDS
TargetSeq CCAGATGAAGACACCCTCATT
NCBI RefSeq NM_175004
Alternative Names PTH; BIT1; PTH2; PTH 2; CFAP37; IMNEPD; CGI-147
Titer >1*10^10 GC/mL
Related Diseases Pancreatic disease (INMEPD)
Target Gene
Gene ID 51651
Uniprot ID Q9Y3E5

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